Nature and function of insulator protein binding sites in the Drosophila genome

Chromatin insulator elements and associated proteins have been proposed to partition eukaryotic genomes into sets of independently regulated domains. Here we test this hypothesis by quantitative genome-wide analysis of insulator protein binding to Drosophila chromatin. We find distinct combinatorial...

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Autores principales: Schwartz, Yuri B., Linder-Basso, Daniela, Kharchenko, Peter V., Tolstorukov, Michael Y., Kim, Maria, Li, Hua-Bing, Gorchakov, Andrey A., Minoda, Aki, Shanower, Gregory, Alekseyenko, Artyom A., Riddle, Nicole C., Jung, Youngsook L., Gu, Tingting, Plachetka, Annette, Elgin, Sarah C.R., Kuroda, Mitzi I., Park, Peter J., Savitsky, Mikhail, Karpen, Gary H., Pirrotta, Vincenzo
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483548/
https://ncbi.nlm.nih.gov/pubmed/22767387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.138156.112
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