Nature and function of insulator protein binding sites in the Drosophila genome

Chromatin insulator elements and associated proteins have been proposed to partition eukaryotic genomes into sets of independently regulated domains. Here we test this hypothesis by quantitative genome-wide analysis of insulator protein binding to Drosophila chromatin. We find distinct combinatorial...

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Main Authors: Schwartz, Yuri B., Linder-Basso, Daniela, Kharchenko, Peter V., Tolstorukov, Michael Y., Kim, Maria, Li, Hua-Bing, Gorchakov, Andrey A., Minoda, Aki, Shanower, Gregory, Alekseyenko, Artyom A., Riddle, Nicole C., Jung, Youngsook L., Gu, Tingting, Plachetka, Annette, Elgin, Sarah C.R., Kuroda, Mitzi I., Park, Peter J., Savitsky, Mikhail, Karpen, Gary H., Pirrotta, Vincenzo
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483548/
https://ncbi.nlm.nih.gov/pubmed/22767387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.138156.112
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