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Reciprocal interactions of human C10orf12 and C17orf96 with PRC2 revealed by BioTAP-XL cross-linking and affinity purification

Understanding the composition of epigenetic regulators remains an important challenge in chromatin biology. Traditional biochemical analysis of chromatin-associated complexes requires their release from DNA under conditions that can also disrupt key interactions. Here we develop a complementary appr...

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Main Authors: Alekseyenko, Artyom A., Gorchakov, Andrey A., Kharchenko, Peter V., Kuroda, Mitzi I.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932854/
https://ncbi.nlm.nih.gov/pubmed/24550272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400648111
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