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Sequence-specific targeting of MSL complex regulates transcription of the roX RNA genes

In Drosophila, dosage compensation is controlled by the male-specific lethal (MSL) complex consisting of at least five proteins and two noncoding RNAs, roX1 and roX2. The roX RNAs function in targeting MSL complex to the X chromosome, and roX transgenes can nucleate spreading of the MSL complex into...

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Autori principali: Bai, Xiaoying, Alekseyenko, Artyom A, Kuroda, Mitzi I
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC514957/
https://ncbi.nlm.nih.gov/pubmed/15229655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600299
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