Nature and function of insulator protein binding sites in the Drosophila genome

Chromatin insulator elements and associated proteins have been proposed to partition eukaryotic genomes into sets of independently regulated domains. Here we test this hypothesis by quantitative genome-wide analysis of insulator protein binding to Drosophila chromatin. We find distinct combinatorial...

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Detalhes bibliográficos
Main Authors: Schwartz, Yuri B., Linder-Basso, Daniela, Kharchenko, Peter V., Tolstorukov, Michael Y., Kim, Maria, Li, Hua-Bing, Gorchakov, Andrey A., Minoda, Aki, Shanower, Gregory, Alekseyenko, Artyom A., Riddle, Nicole C., Jung, Youngsook L., Gu, Tingting, Plachetka, Annette, Elgin, Sarah C.R., Kuroda, Mitzi I., Park, Peter J., Savitsky, Mikhail, Karpen, Gary H., Pirrotta, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483548/
https://ncbi.nlm.nih.gov/pubmed/22767387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.138156.112
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