A Randomized Controlled Trial to Evaluate the Effects of High-Dose versus Low-Dose of Arginine Therapy on Hepatic Function Tests in Argininosuccinic Aciduria

OBJECTIVE: To compare the effects of combinatorial therapy with low-dose arginine and a nitrogen scavenging agent (sodium phenylbutyrate) vs. monotherapy with high-dose arginine on liver function tests in patients with argininosuccinic aciduria (ASA). STUDY DESIGN: Twelve patients with ASA were enro...

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Main Authors: Nagamani, Sandesh CS, Shchelochkov, Oleg A, Mullins, Mary A, Carter, Susan, Lanpher, Brendan C., Sun, Qin, Kleppe, Soledad, Erez, Ayelet, Smith, E O’Brian, Marini, Juan, Lee, Brendan
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483446/
https://ncbi.nlm.nih.gov/pubmed/23040521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2012.09.016
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