Nitric-Oxide Supplementation for Treatment of Long-Term Complications in Argininosuccinic Aciduria

Argininosuccinate lyase (ASL) is required for the synthesis and channeling of L-arginine to nitric oxide synthase (NOS) for nitric oxide (NO) production. Congenital ASL deficiency causes argininosuccinic aciduria (ASA), the second most common urea-cycle disorder, and leads to deficiency of both urea...

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Main Authors: Nagamani, Sandesh C.S., Campeau, Philippe M., Shchelochkov, Oleg A., Premkumar, Muralidhar H., Guse, Kilian, Brunetti-Pierri, Nicola, Chen, Yuqing, Sun, Qin, Tang, Yaoping, Palmer, Donna, Reddy, Anilkumar K., Li, Li, Slesnick, Timothy C., Feig, Daniel I., Caudle, Susan, Harrison, David, Salviati, Leonardo, Marini, Juan C., Bryan, Nathan S., Erez, Ayelet, Lee, Brendan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376491/
https://ncbi.nlm.nih.gov/pubmed/22541557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.03.018
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