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Morphological and molecular changes in aging rat prelimbic prefrontal cortical synapses

Age-related impairments of executive functions appear to be related to reductions of the number and plasticity of dendritic spine synapses in the prefrontal cortex (PFC). Experimental evidence suggests that synaptic plasticity is mediated by the spine actin cytoskeleton, and a major pathway regulati...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bloss, Erik B., Puri, Rishi, Yuk, Frank, Punsoni, Michael, Hara, Yuko, Janssen, William G., McEwen, Bruce S., Morrison, John H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483440/
https://ncbi.nlm.nih.gov/pubmed/22727942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.05.014
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