Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression

Genome-wide association studies (GWASs) have identified thousands of single nucleotide polymorphisms (SNPs) associated with human traits and diseases. But because the vast majority of these SNPs are located in the noncoding regions of the genome their risk promoting mechanisms are elusive. Employing...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Cowper-Sal·lari, Richard, Zhang, Xiaoyang, Wright, Jason B., Bailey, Swneke D., Cole, Michael D., Eeckhoute, Jerome, Moore, Jason H., Lupien, Mathieu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483423/
https://ncbi.nlm.nih.gov/pubmed/23001124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2416
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge