Splenic Red Pulp Macrophages Produce Type I Interferons as Early Sentinels of Malaria Infection but Are Dispensable for Control

Type I interferons (T1IFNs) are among the earliest cytokines produced during infections due to their direct regulation by innate immune signaling pathways. Reports have suggested that T1IFNs are produced during malaria infection, but little is known about the in vivo cellular origins of T1IFNs or th...

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Hlavní autoři: Kim, Charles C., Nelson, Christopher S., Wilson, Emily B., Hou, Baidong, DeFranco, Anthony L., DeRisi, Joseph L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483282/
https://ncbi.nlm.nih.gov/pubmed/23144737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048126
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