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Critical role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis

Tissue macrophages comprise a heterogeneous group of cell types differing in location, surface markers and function1. Red pulp macrophages are a distinct splenic subset involved in removing senescent red blood cells2. Transcription factors such as PU.1 and C/EBPα play general roles in myelomonocytic...

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Detalhes bibliográficos
Main Authors: Kohyama, Masako, Ise, Wataru, Edelson, Brian T., Wilker, Peter R., Hildner, Kai, Mejia, Carlo, Frazier, William A., Murphy, Theresa L., Murphy, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756102/
https://ncbi.nlm.nih.gov/pubmed/19037245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07472
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