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Increased uptake by splenic red pulp macrophages contributes to rapid platelet turnover in WASP(−) mice
Thrombocytopenia due to rapid platelet consumption contributes to the severe thrombocytopenia of the Wiskott Aldrich Syndrome (WAS), and to the milder thrombocytopenia seen in murine WAS. Here we show that rapid clearance of (111)In labeled murine WASP(−) platelets correlates with enhanced splenic u...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3884558/ https://ncbi.nlm.nih.gov/pubmed/23727585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.05.003 |
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