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PGD(2)-CRTH2 Pathway Promotes Tubulointerstitial Fibrosis
Urinary excretion of lipocalin-type PGD(2) synthase (L-PGDS), which converts PG H(2) to PGD(2), increases in early diabetic nephropathy. In addition, L-PGDS expression in the tubular epithelium increases in adriamycin-induced nephropathy, suggesting that locally produced L-PGDS may promote the devel...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482731/ https://ncbi.nlm.nih.gov/pubmed/22997255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012020126 |
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