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Dual Functions of Prostaglandin D2 in Murine Contact Hypersensitivity via DP and CRTH2

Prostaglandin D2 (PGD2) exerts its effects through two distinct receptors: the chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) and the D prostanoid (DP) receptor. Our previous study demonstrated that CRTH2 mediates contact hypersensitivity (CHS) in mice. However, the func...

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Detalhes bibliográficos
Main Authors: Yamamoto, Yoshihiro, Otani, Shinobu, Hirai, Hiroyuki, Nagata, Kinya, Aritake, Kosuke, Urade, Yoshihiro, Narumiya, Shuh, Yokozeki, Hiroo, Nakamura, Masataka, Satoh, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123801/
https://ncbi.nlm.nih.gov/pubmed/21703412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.03.047
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