Dendritic Cells Express Hematopoietic Prostaglandin D Synthase and Function as a Source of Prostaglandin D2 in the Skin

Prostaglandin D2 (PGD2), an arachidonic acid metabolite, has been implicated in allergic responses. A major source of PGD2 in the skin is mast cells that express hematopoietic PGD synthase (H-PGDS). In this study, we show the expression of H-PGDS in human dendritic cells (DCs) and the regulatory mec...

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Detalhes bibliográficos
Main Authors: Shimura, Chieko, Satoh, Takahiro, Igawa, Ken, Aritake, Kosuke, Urade, Yoshihiro, Nakamura, Masataka, Yokozeki, Hiroo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797885/
https://ncbi.nlm.nih.gov/pubmed/20008150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090111
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