Improvement in the quality of hematopoietic prostaglandin D synthase crystals in a microgravity environment

Human hematopoietic prostaglandin synthase, one of the better therapeutic target enzymes for allergy and inflammation, was crystallized with 22 inhibitors and in three inhibitor-free conditions in microgravity. Most of the space-grown crystals showed better X-ray diffraction patterns than the terres...

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Detalhes bibliográficos
Main Authors: Tanaka, Hiroaki, Tsurumura, Toshiharu, Aritake, Kosuke, Furubayashi, Naoki, Takahashi, Sachiko, Yamanaka, Mari, Hirota, Erika, Sano, Satoshi, Sato, Masaru, Kobayashi, Tomoyuki, Tanaka, Tetsuo, Inaka, Koji, Urade, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Diffraction Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004263/
https://ncbi.nlm.nih.gov/pubmed/21169700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0909049510037076
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