Structural Basis of the Catalytic Mechanism Operating in Open-Closed Conformers of Lipocalin Type Prostaglandin D Synthase

Lipocalin type prostaglandin D synthase (L-PGDS) is a multifunctional protein acting as a somnogen (PGD(2))-producing enzyme, an extracellular transporter of various lipophilic ligands, and an amyloid-β chaperone in human cerebrospinal fluid. In this study, we determined the crystal structures of tw...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kumasaka, Takashi, Aritake, Kosuke, Ago, Hideo, Irikura, Daisuke, Tsurumura, Toshiharu, Yamamoto, Masaki, Miyano, Masashi, Urade, Yoshihiro, Hayaishi, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755957/
https://ncbi.nlm.nih.gov/pubmed/19546224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018341
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados