Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model

BACKGROUND: Duchenne muscular dystrophy is a genetic disease involving a severe muscle wasting that is characterized by cycles of muscle degeneration/regeneration and culminates in early death in affected boys. Mitochondria are presumed to be involved in the regulation of myoblast proliferation/diff...

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Main Authors: Jahnke, Vanessa E, Van Der Meulen, Jack H, Johnston, Helen K, Ghimbovschi, Svetlana, Partridge, Terrence, Hoffman, Eric P, Nagaraju, Kanneboyina
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2012
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482394/
https://ncbi.nlm.nih.gov/pubmed/22908954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2044-5040-2-16
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