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Primary phagocytosis of viable neurons by microglia activated with LPS or Aβ is dependent on calreticulin/LRP phagocytic signalling

BACKGROUND: Microglia are resident brain macrophages that can phagocytose dead, dying or viable neurons, which may be beneficial or detrimental in inflammatory, ischaemic and neurodegenerative brain pathologies. Cell death caused by phagocytosis of an otherwise viable cell is called ‘primary phagocy...

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Main Authors: Fricker, Michael, Oliva-Martín, María José, Brown, Guy C
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481398/
https://ncbi.nlm.nih.gov/pubmed/22889139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-196
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