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MFG-E8 Mediates Primary Phagocytosis of Viable Neurons during Neuroinflammation

Milk-fat globule EGF factor-8 (MFG-E8, SED1, lactadherin) is known to mediate the phagocytic removal of apoptotic cells by bridging phosphatidylserine (PS)-exposing cells and the vitronectin receptor (VR) on phagocytes. However, we show here that MFG-E8 can mediate phagocytosis of viable neurons dur...

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Bibliografiske detaljer
Main Authors: Fricker, Michael, Neher, Jonas J., Zhao, Jing-Wei, Théry, Clotilde, Tolkovsky, Aviva M., Brown, Guy C.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312099/
https://ncbi.nlm.nih.gov/pubmed/22357850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4837-11.2012
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