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Primary phagocytosis of viable neurons by microglia activated with LPS or Aβ is dependent on calreticulin/LRP phagocytic signalling

BACKGROUND: Microglia are resident brain macrophages that can phagocytose dead, dying or viable neurons, which may be beneficial or detrimental in inflammatory, ischaemic and neurodegenerative brain pathologies. Cell death caused by phagocytosis of an otherwise viable cell is called ‘primary phagocy...

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Bibliografische gegevens
Hoofdauteurs: Fricker, Michael, Oliva-Martín, María José, Brown, Guy C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481398/
https://ncbi.nlm.nih.gov/pubmed/22889139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-196
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