Ceramide Glycosylation by Glucosylceramide Synthase Selectively Maintains the Properties of Breast Cancer Stem Cells

Cancer stem cells are distinguished from normal adult stem cells by their stemness without tissue homeostasis control. Glycosphingolipids (GSLs), particularly globo-series GSLs, are important markers of undifferentiated embryonic stem cells, but little is known about whether or not ceramide glycosyl...

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Główni autorzy: Gupta, Vineet, Bhinge, Kaustubh N., Hosain, Salman B., Xiong, Katherine, Gu, Xin, Shi, Runhua, Ho, Ming-Yi, Khoo, Kay-Hooi, Li, Su-Chen, Li, Yu-Teh, Ambudkar, Suresh V., Jazwinski, S. Michal, Liu, Yong-Yu
Format: Artigo
Język:Inglês
Wydane: American Society for Biochemistry and Molecular Biology 2012
Hasła przedmiotowe:
Cell Biology
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481319/
https://ncbi.nlm.nih.gov/pubmed/22936806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.396390
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