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The adaptor protein FADD and the initiator caspase-8 mediate activation of NF-κB by TRAIL
Besides inducing apoptosis, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) activates NF-κB. The apoptosis signaling pathway of TRAIL is well characterized involving TRAIL receptors, Fas-associated protein with death domain (FADD) and caspase-8. In contrast, the molecular mechanism o...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3481141/ https://ncbi.nlm.nih.gov/pubmed/23096115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.154 |
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