Loading...
Caspase-8 and c-FLIP(L) Associate in Lipid Rafts with NF-κB Adaptors during T Cell Activation
Humans and mice lacking functional caspase-8 in T cells manifest a profound immunodeficiency syndrome due to defective T cell antigen receptor (TCR)-induced NF-κB signaling and proliferation. It is unknown how caspase-8 is activated following T cell stimulation, and what is the caspase-8 substrate(s...
Saved in:
| Published in: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4521413/ https://ncbi.nlm.nih.gov/pubmed/17462996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M610610200 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|