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Caspase-8 and c-FLIP(L) Associate in Lipid Rafts with NF-κB Adaptors during T Cell Activation
Humans and mice lacking functional caspase-8 in T cells manifest a profound immunodeficiency syndrome due to defective T cell antigen receptor (TCR)-induced NF-κB signaling and proliferation. It is unknown how caspase-8 is activated following T cell stimulation, and what is the caspase-8 substrate(s...
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| 發表在: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4521413/ https://ncbi.nlm.nih.gov/pubmed/17462996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M610610200 |
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