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c-FLIP(S) reduces activation of caspase and NF-κB pathways and decreases T cell survival
Effective stimulation of NF-κB in T cells following TCR ligation requires the activity of caspase-8. The active caspase-8 complex includes the paracaspase, MALT1, and Bcl-10, which connect to the NF-κB pathway. It has been less clear what regulates the level of caspase-8 activity during T cell activ...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756655/ https://ncbi.nlm.nih.gov/pubmed/18081036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200636956 |
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