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Aβ oligomer toxicity inhibitor protects memory in models of synaptic toxicity
BACKGROUND AND PURPOSE: Amyloid-β (Aβ) aggregation into synaptotoxic, prefibrillar oligomers is a major pathogenic event underlying the neuropathology of Alzheimer's disease (AD). The pharmacological and neuroprotective properties of a novel Aβ aggregation inhibitor, SEN1269, were investigated...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Blackwell Publishing Ltd
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3481045/ https://ncbi.nlm.nih.gov/pubmed/22913627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01973.x |
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