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A2E accumulation influences retinal microglial activation and complement regulation

Age-related macular degeneration (AMD) is an outer retinal disease that involves aging and immune dysfunction. In the aging retina, microglia aggregate in the outer retina and acquire intracellular autofluorescent lipofuscin deposits. In this study, we investigated whether accumulation of A2E, a key...

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Bibliografski detalji
Glavni autori: Ma, Wenxin, Coon, Steven, Zhao, Lian, Fariss, Robert N., Wong, Wai T.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480997/
https://ncbi.nlm.nih.gov/pubmed/22819137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.06.010
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