Microglial phagocytosis and activation underlying photoreceptor degeneration is regulated by CX3CL1‐CX3CR1 signaling in a mouse model of retinitis pigmentosa

Retinitis pigmentosa (RP), a disease characterized by the progressive degeneration of mutation‐bearing photoreceptors, is a significant cause of incurable blindness in the young worldwide. Recent studies have found that activated retinal microglia contribute to photoreceptor demise via phagocytosis...

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Bibliografiske detaljer
Udgivet i:Glia
Main Authors: Zabel, Matthew K., Zhao, Lian, Zhang, Yikui, Gonzalez, Shaimar R., Ma, Wenxin, Wang, Xu, Fariss, Robert N., Wong, Wai T.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958518/
https://ncbi.nlm.nih.gov/pubmed/27314452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23016
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