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C3- and CR3-dependent microglial clearance protects photoreceptors in retinitis pigmentosa
Complement activation has been implicated as contributing to neurodegeneration in retinal and brain pathologies, but its role in retinitis pigmentosa (RP), an inherited and largely incurable photoreceptor degenerative disease, is unclear. We found that multiple complement components were markedly up...
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| Udgivet i: | J Exp Med |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Rockefeller University Press
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6683998/ https://ncbi.nlm.nih.gov/pubmed/31209071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190009 |
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