Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism

BACKGROUND & AIMS: Pathogenesis of cirrhosis, a disabling outcome of defective liver repair, involves deregulated accumulation of myofibroblasts derived from quiescent hepatic stellate cells (HSC), but the mechanisms that control HSC transdifferentiation are poorly understood. We investigated wh...

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Detalhes bibliográficos
Main Authors: Chen, Yuping, Choi, Steve S., Michelotti, Gregory A., Chan, Isaac S., Swiderska, Marzena, Karaca, Gamze F., Xie, Guanhua, Moylan, Cynthia A., Garibaldi, Francesca, Premont, Richard, Suliman, Hagir B., Piantodosi, Claude A., Diehl, Anna Mae
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480563/
https://ncbi.nlm.nih.gov/pubmed/22885334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.07.115
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