Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism

BACKGROUND & AIMS: Pathogenesis of cirrhosis, a disabling outcome of defective liver repair, involves deregulated accumulation of myofibroblasts derived from quiescent hepatic stellate cells (HSC), but the mechanisms that control HSC transdifferentiation are poorly understood. We investigated wh...

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Autors principals: Chen, Yuping, Choi, Steve S., Michelotti, Gregory A., Chan, Isaac S., Swiderska, Marzena, Karaca, Gamze F., Xie, Guanhua, Moylan, Cynthia A., Garibaldi, Francesca, Premont, Richard, Suliman, Hagir B., Piantodosi, Claude A., Diehl, Anna Mae
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480563/
https://ncbi.nlm.nih.gov/pubmed/22885334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.07.115
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