Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism

BACKGROUND & AIMS: Pathogenesis of cirrhosis, a disabling outcome of defective liver repair, involves deregulated accumulation of myofibroblasts derived from quiescent hepatic stellate cells (HSC), but the mechanisms that control HSC transdifferentiation are poorly understood. We investigated wh...

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Главные авторы: Chen, Yuping, Choi, Steve S., Michelotti, Gregory A., Chan, Isaac S., Swiderska, Marzena, Karaca, Gamze F., Xie, Guanhua, Moylan, Cynthia A., Garibaldi, Francesca, Premont, Richard, Suliman, Hagir B., Piantodosi, Claude A., Diehl, Anna Mae
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480563/
https://ncbi.nlm.nih.gov/pubmed/22885334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.07.115
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