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Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics

Activation of the sonic hedgehog (Shh) pathway is required for the growth of numerous tissues and organs and recent evidence indicates that this pathway is often recruited to stimulate growth of cancer stem cells (CSCs) and to orchestrate the reprogramming of cancer cells via epithelial mesenchymal...

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Detalhes bibliográficos
Main Authors: Tang, Su-Ni, Fu, Junsheng, Nall, Dara, Rodova, Mariana, Shankar, Sharmila, Srivastava, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480310/
https://ncbi.nlm.nih.gov/pubmed/21796625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26323
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