Resveratrol Inhibits Pancreatic Cancer Stem Cell Characteristics in Human and Kras(G12D) Transgenic Mice by Inhibiting Pluripotency Maintaining Factors and Epithelial-Mesenchymal Transition

BACKGROUND: Cancer stem cells (CSCs) can proliferate and self-renew extensively due to their ability to express anti-apoptotic and drug resistant proteins, thus sustaining tumor growth. Therefore, the strategy to eradicate CSCs might have significant clinical implications. The objectives of this stu...

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Detalhes bibliográficos
Main Authors: Shankar, Sharmila, Nall, Dara, Tang, Su-Ni, Meeker, Daniel, Passarini, Jenna, Sharma, Jay, Srivastava, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031576/
https://ncbi.nlm.nih.gov/pubmed/21304978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016530
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