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Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action

Existing drugs have limited efficacy against the rising threat of drug-resistant TB, have significant side effects, and must be given in combinations of four to six drugs for at least 6 months for drug-sensitive TB and up to 24 months for drug-resistant TB. The long treatment duration has led to inc...

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Huvudupphovsmän: Sacksteder, Katherine A, Protopopova, Marina, Barry, Clifton E, Andries, Koen, Nacy, Carol A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480206/
https://ncbi.nlm.nih.gov/pubmed/22827305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb.12.56
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