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Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

We previously reported the discovery of P7C3, an aminopropyl carbazole having proneurogenic and neuroprotective properties in newborn neural precursor cells of the hippocampal dentate gyrus. We have further found that chemicals having efficacy in this in vivo screening assay also protect dopaminergi...

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Detalhes bibliográficos
Main Authors: Tesla, Rachel, Wolf, Hamilton Parker, Xu, Pin, Drawbridge, Jordan, Estill, Sandi Jo, Huntington, Paula, McDaniel, LaTisha, Knobbe, Whitney, Burket, Aaron, Tran, Stephanie, Starwalt, Ruth, Morlock, Lorraine, Naidoo, Jacinth, Williams, Noelle S., Ready, Joseph M., McKnight, Steven L., Pieper, Andrew A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479516/
https://ncbi.nlm.nih.gov/pubmed/23027932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213960109
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