Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

We previously reported the discovery of P7C3, an aminopropyl carbazole having proneurogenic and neuroprotective properties in newborn neural precursor cells of the hippocampal dentate gyrus. We have further found that chemicals having efficacy in this in vivo screening assay also protect dopaminergi...

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Main Authors: Tesla, Rachel, Wolf, Hamilton Parker, Xu, Pin, Drawbridge, Jordan, Estill, Sandi Jo, Huntington, Paula, McDaniel, LaTisha, Knobbe, Whitney, Burket, Aaron, Tran, Stephanie, Starwalt, Ruth, Morlock, Lorraine, Naidoo, Jacinth, Williams, Noelle S., Ready, Joseph M., McKnight, Steven L., Pieper, Andrew A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479516/
https://ncbi.nlm.nih.gov/pubmed/23027932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213960109
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