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Impact of base pair identity 5′ to the spliceosomal branch site adenosine on branch site conformation

The branch site helix from Saccharomyces cerevisiae with pseudouridine (ψ) incorporated in a phylogenetically conserved position of U2 snRNA features an extrahelical branch site adenosine (A) that forms a base triple interaction with the minor groove edge of a widely conserved purine(U2 strand)-pyri...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Popović, Milena, Nelson, Joycelynn D., Schroeder, Kersten T., Greenbaum, Nancy L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479398/
https://ncbi.nlm.nih.gov/pubmed/23002123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.035782.112
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