Translation termination efficiency modulates ATF4 response by regulating ATF4 mRNA translation at 5′ short ORFs

The activating transcription factor 4 (ATF4) promotes transcriptional upregulation of specific target genes in response to cellular stress. ATF4 expression is regulated at the translational level by two short open reading frames (uORFs) in its 5′-untranslated region (5′-UTR). Here, we describe a mec...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ait Ghezala, Hayet, Jolles, Béatrice, Salhi, Samia, Castrillo, Katia, Carpentier, Wassila, Cagnard, Nicolas, Bruhat, Alain, Fafournoux, Pierre, Jean-Jean, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479206/
https://ncbi.nlm.nih.gov/pubmed/22904092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks762
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados