The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

In response to different environmental stresses, eIF2α phosphorylation represses global translation coincident with preferential translation of ATF4, a master regulator controlling the transcription of key genes essential for adaptative functions. Here, we establish that the eIF2α/ATF4 pathway direc...

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Detalhes bibliográficos
Main Authors: B’chir, Wafa, Maurin, Anne-Catherine, Carraro, Valérie, Averous, Julien, Jousse, Céline, Muranishi, Yuki, Parry, Laurent, Stepien, Georges, Fafournoux, Pierre, Bruhat, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763548/
https://ncbi.nlm.nih.gov/pubmed/23804767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt563
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