Deoxycytidine kinase regulates the G2/M checkpoint through interaction with cyclin-dependent kinase 1 in response to DNA damage

Deoxycytidine kinase (dCK) is a rate limiting enzyme critical for phosphorylation of endogenous deoxynucleosides for DNA synthesis and exogenous nucleoside analogues for anticancer and antiviral drug actions. dCK is activated in response to DNA damage; however, how it functions in the DNA damage res...

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Detalhes bibliográficos
Main Authors: Yang, Chunying, Lee, Michael, Hao, Jianwei, Cui, Xiaoli, Guo, Xiaojing, Smal, Caroline, Bontemps, Françoise, Ma, Shumei, Liu, Xiaodong, Engler, David, Parker, William B., Xu, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479177/
https://ncbi.nlm.nih.gov/pubmed/22850745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks707
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