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A Large Extension to HIV-1 Gag, Like Pol, Has Negative Impacts on Virion Assembly

The GagPol protein of HIV-1 harbors viral enzymes, such as protease (PR), reverse transcriptase, and integrase, that are all crucial for virion infectivity. Previous studies have suggested that expression of GagPol alone does not produce viral particles and that the budding defect is caused by the p...

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Bibliografske podrobnosti
Main Authors: Haraguchi, Hiyori, Noda, Takeshi, Kawaoka, Yoshihiro, Morikawa, Yuko
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479142/
https://ncbi.nlm.nih.gov/pubmed/23110110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047828
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