Dominant Negative Inhibition of Human Immunodeficiency Virus Particle Production by the Nonmyristoylated Form of Gag

Myristoylation of human immunodeficiency virus (HIV) Gag protein is essential for membrane targeting of Gag and production of viral particles. We show here that coexpression of wild-type and nonmyristoylated forms of HIV Gag resulted in severe inhibition of viral particle production, indicating that...

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Bibliografiske detaljer
Main Authors: Kawada, Shigeo, Goto, Toshiyuki, Haraguchi, Hiyori, Ono, Akira, Morikawa, Yuko
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Structure and Assembly
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293052/
https://ncbi.nlm.nih.gov/pubmed/18305041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01953-07
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