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Dominant Negative Inhibition of Human Immunodeficiency Virus Particle Production by the Nonmyristoylated Form of Gag

Myristoylation of human immunodeficiency virus (HIV) Gag protein is essential for membrane targeting of Gag and production of viral particles. We show here that coexpression of wild-type and nonmyristoylated forms of HIV Gag resulted in severe inhibition of viral particle production, indicating that...

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Detalhes bibliográficos
Main Authors: Kawada, Shigeo, Goto, Toshiyuki, Haraguchi, Hiyori, Ono, Akira, Morikawa, Yuko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293052/
https://ncbi.nlm.nih.gov/pubmed/18305041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01953-07
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