Efavirenz Enhances HIV-1 Gag Processing at the Plasma Membrane through Gag-Pol Dimerization

Efavirenz (EFV), a nonnucleoside reverse transcriptase (RT) inhibitor, also inhibits HIV-1 particle release through enhanced Gag/Gag-Pol processing by protease (PR). To better understand the mechanisms of the EFV-mediated enhancement of Gag processing, we examined the intracellular localization of G...

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Detalhes bibliográficos
Main Authors: Sudo, Sho, Haraguchi, Hiyori, Hirai, Yoko, Gatanaga, Hiroyuki, Sakuragi, Jun-ichi, Momose, Fumitaka, Morikawa, Yuko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592135/
https://ncbi.nlm.nih.gov/pubmed/23302874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02306-12
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