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A Large Extension to HIV-1 Gag, Like Pol, Has Negative Impacts on Virion Assembly
The GagPol protein of HIV-1 harbors viral enzymes, such as protease (PR), reverse transcriptase, and integrase, that are all crucial for virion infectivity. Previous studies have suggested that expression of GagPol alone does not produce viral particles and that the budding defect is caused by the p...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479142/ https://ncbi.nlm.nih.gov/pubmed/23110110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047828 |
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