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Conserved small protein associates with the multidrug efflux pump AcrB and differentially affects antibiotic resistance
The AcrAB–TolC multidrug efflux pump confers resistance to a wide variety of antibiotics and other compounds in Escherichia coli. Here we show that AcrZ (formerly named YbhT), a 49-amino-acid inner membrane protein, associates with the AcrAB-TolC complex. Co-purification of AcrZ with AcrB, in the ab...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478662/ https://ncbi.nlm.nih.gov/pubmed/23010927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210093109 |
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