Conserved small protein associates with the multidrug efflux pump AcrB and differentially affects antibiotic resistance

The AcrAB–TolC multidrug efflux pump confers resistance to a wide variety of antibiotics and other compounds in Escherichia coli. Here we show that AcrZ (formerly named YbhT), a 49-amino-acid inner membrane protein, associates with the AcrAB-TolC complex. Co-purification of AcrZ with AcrB, in the ab...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hobbs, Errett C., Yin, Xuefeng, Paul, Brian J., Astarita, Jillian L., Storz, Gisela
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478662/
https://ncbi.nlm.nih.gov/pubmed/23010927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210093109
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg