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Nicastrin regulates breast cancer stem cell properties and tumor growth in vitro and in vivo
Nicastrin (NCT) is a crucial component of the γ-secretase (GS) enzyme, which prompted investigations into its biological role in cancer. We have previously shown that nicastrin is overexpressed in breast cancer (BC), conferring worse overall survival in invasive, ERα negative patients. Here, we used...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478621/ https://ncbi.nlm.nih.gov/pubmed/23012411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206268109 |
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