Anti-nicastrin monoclonal antibodies elicit pleiotropic anti-tumour pharmacological effects in invasive breast cancer cells

The goal of targeted cancer therapies is to specifically block oncogenic signalling, thus maximising efficacy, while reducing side-effects to patients. The gamma-secretase (GS) complex is an attractive therapeutic target in haematological malignancies and solid tumours with major pharmaceutical acti...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Filipović, Aleksandra, Lombardo, Ylenia, Fronato, Monica, Abrahams, Joel, Aboagye, Eric, Nguyen, Quang-De, d’Aqua, Barbara Borda, Ridley, Anne, Green, Andrew, Rahka, Emad, Ellis, Ian, Recchi, Chiara, Przulj, Natasa, Sarajlić, Anida, Alattia, Jean-Rene, Fraering, Patrick, Deonarain, Mahendra, Coombes, R. Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223543/
https://ncbi.nlm.nih.gov/pubmed/25248409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-3119-z
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