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Subsets of non-clonal neighboring CD4(+) T cells specifically regulate the frequency of individual antigen-reactive T cells
After an immune response, the expanded population of antigen-specific CD4+ T cells contract to steady-state levels. We have found that the contraction is neither cell-autonomous nor mediated by competition for generic trophic factors, but regulated by relatively rare subsets of neighboring CD4(+) T...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478444/ https://ncbi.nlm.nih.gov/pubmed/23021952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.08.008 |
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